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Clin Infect Dis. 2011 Jan 1;52(1):94-6. doi: 10.1093/cid/ciq072.

Oral treatment for Mycobacterium ulcerans infection: results from a pilot study in Benin.

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  • 1Centre de Diagnostic et de Traitement de l'Ulcère de Buruli, Pobè, Bénin.


Mycobacterium ulcerans infection is responsible for severe skin lesions in sub-Saharan Africa. We enrolled 30 Beninese patients with Buruli ulcers in a pilot study to evaluate efficacy of an oral chemotherapy using rifampicin plus clarithromycin during an 8-week period. The treatment was well tolerated, and all patients were healed by 12 months after initiation of therapy without relapse.

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