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Am J Surg. 2010 Dec;200(6):719-22; disussion 722-3. doi: 10.1016/j.amjsurg.2010.07.023.

Antibiotic prophylaxis in the placement of totally implanted central venous access ports.

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  • 1Department of Surgery, University of Utah, East Salt Lake City, UT 84132, USA. courtney.scaife@hsc.utah.edu

Abstract

BACKGROUND:

Antibiotic prophylaxis during placement of implanted central venous access ports (CVAP) has not been studied. This retrospective review compared the rate of catheter-related infections (CRIs) with and without perioperative antibiotics.

METHODS:

This was a single-center study that compared patients treated with and without a single dose of antibiotics during CVAP placement. CRIs were defined as a patient treated with antibiotics for port site induration, positive blood cultures, or suspicion of infection that led to port removal within 30 days of placement.

RESULTS:

CVAP were placed in 459 patients, 103 of whom (22.4%) received antibiotic prophylaxis. Surgical technique and patient demographics were similar to those patients not receiving antibiotics (356). All 9 (2%) CRIs occurred in the non-prophylactic antibiotic group (P = .218), with 5 infections resulting in port removal.

CONCLUSIONS:

Single-dose perioperative antibiotics may decrease CVAP infection rates and should be studied further in a prospective randomized trial.

Copyright © 2010 Elsevier Inc. All rights reserved.

PMID:
21146010
[PubMed - indexed for MEDLINE]
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