Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Heredity (Edinb). 2011 Jul;107(1):1-15. doi: 10.1038/hdy.2010.152. Epub 2010 Dec 8.

Applications of next generation sequencing in molecular ecology of non-model organisms.

Author information

  • 1Department of Animal and Plant Sciences, University of Sheffield, UK. robert.ekblom@ebc.uu.se

Abstract

As most biologists are probably aware, technological advances in molecular biology during the last few years have opened up possibilities to rapidly generate large-scale sequencing data from non-model organisms at a reasonable cost. In an era when virtually any study organism can 'go genomic', it is worthwhile to review how this may impact molecular ecology. The first studies to put the next generation sequencing (NGS) to the test in ecologically well-characterized species without previous genome information were published in 2007 and the beginning of 2008. Since then several studies have followed in their footsteps, and a large number are undoubtedly under way. This review focuses on how NGS has been, and can be, applied to ecological, population genetic and conservation genetic studies of non-model species, in which there is no (or very limited) genomic resources. Our aim is to draw attention to the various possibilities that are opening up using the new technologies, but we also highlight some of the pitfalls and drawbacks with these methods. We will try to provide a snapshot of the current state of the art for this rapidly advancing and expanding field of research and give some likely directions for future developments.

PMID:
21139633
[PubMed - indexed for MEDLINE]
PMCID:
PMC3186121
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Nature Publishing Group Icon for PubMed Central
    Loading ...
    Write to the Help Desk