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Br J Cancer. 2011 Jan 4;104(1):175-7. doi: 10.1038/sj.bjc.6605986. Epub 2010 Nov 30.

Hand pattern indicates prostate cancer risk.

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  • 1Division of Epidemiology and Public Health, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK.



The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels.


We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls.


Compared with index finger shorter than ring finger (low 2Dā€‰:ā€‰4D), men with index finger longer than ring finger (high 2Dā€‰:ā€‰4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57-0.80). Risk reduction was even greater (87%) in age group <60 (OR 0.13, 95% CI 0.09-0.21).


Pattern of finger lengths may be a simple marker of prostate cancer risk, with length of 2D greater than 4D suggestive of lower risk.

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