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J Cancer Res Ther. 2010 Jul-Sep;6(3):388-90. doi: 10.4103/0973-1482.73347.

Neurofibroma of kidney: an uncommon neoplasm and diagnostic dilemma with solitary fibrous tumor.

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  • 1Department of Pathology, Medical College, Kolkata, West Bengal, India. dr_santoshkumar@hotmail.com

Abstract

Neurofibroma of kidney is an extremely rare tumor. To our knowledge, only five such cases have been reported worldwide till date. Here, we report a solitary neurofibroma of right kidney in a 54-year-old woman. Radiological investigations (ultrasonography and computed tomography) detected a solid mass in the upper pole of right kidney and clinicoradiologically renal cell carcinoma was suspected. A radical nephrectomy was performed under diagnosis of cancer. Microscopically, tumor consisted of benign spindle-shaped cells accompanied by fibrous tissue. Differential diagnoses of neurofibroma and solitary fibrous tumor (SFT) were made on morphological features. Immunohistochemically, the tumor cells were positive for S-100 protein, but negative for CD34 and CD99. Thus, a diagnosis of neurofibroma was established.

PMID:
21119287
[PubMed - indexed for MEDLINE]
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