Modeling neuropsychiatric disease-relevant human SNPs in mice

Neuropsychopharmacology. 2011 Jan;36(1):364-5. doi: 10.1038/npp.2010.143.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Brain Chemistry / genetics*
  • Brain-Derived Neurotrophic Factor / genetics
  • Catechol O-Methyltransferase / genetics
  • Disease Models, Animal
  • Gene Expression Regulation / genetics*
  • Gene Knock-In Techniques
  • Genetic Predisposition to Disease / genetics*
  • Humans
  • Mental Disorders / genetics*
  • Mental Disorders / metabolism*
  • Mental Disorders / physiopathology
  • Mice
  • Mice, Mutant Strains
  • Mice, Transgenic
  • Polymorphism, Single Nucleotide / genetics*
  • Receptors, Opioid, mu / genetics

Substances

  • Brain-Derived Neurotrophic Factor
  • OPRM1 protein, human
  • Receptors, Opioid, mu
  • Catechol O-Methyltransferase