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Antimicrob Agents Chemother. 2011 Feb;55(2):934-6. doi: 10.1128/AAC.01247-10. Epub 2010 Nov 29.

Detection of NDM-1-producing Klebsiella pneumoniae in Kenya.

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  • 1Service de Bactériologie-Virologie, INSERM U914 Emerging Resistance to Antibiotics, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris Sud, Le Kremlin-Bicêtre, France.

Abstract

Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla(NDM-1) carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including β-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.

PMID:
21115785
[PubMed - indexed for MEDLINE]
PMCID:
PMC3028766
Free PMC Article
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