J Biol Chem. 1978 Oct 10;253(19):6630-2.

Nonspecific effect of m7GMP on protein-RNA interactions.

Abstract

Cap analogs m7GMP and m7GDP inhibit binding of eukaryotic initiation factors to reovirus capped mRNA but also inhibit complex formation involving uncapped mRNA or 18 S rRNA. Furthermore, Escherichia coli DNA-dependent RNA polymerase binds 18 S rRNA and this interaction is also blocked by m7GMP. These results indicate that inhibition by cap analogs is not a stringent test for putative cap-specific binding between proteins and mRNA.

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Diminished sensitivity of re-initiation of translation to inhibition by cap analogues in reticulocyte lysates. [Eur J Biochem. 1978]
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Asselbergs FA, Peters W, Venrooij WJ, Bloemendal H. Eur J Biochem. 1978 Aug 1; 88(2):483-8.
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Cited by 8 PubMed Central articles

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Nonspecific effect of m7GMP on protein-RNA interactions.

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