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Clin Vaccine Immunol. 2011 Jan;18(1):176-9. doi: 10.1128/CVI.00007-10. Epub 2010 Nov 24.

Synthetic double-stranded RNA stimulates the expression of interferon-inducible protein 10 in human mesothelial cells.

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  • 1Klinikum Traunstein, Nephrology, Cuno-Niggl-Str. 3, 83278 Traunstein, Germany.

Abstract

Interferon-inducible protein 10 (IP-10) is a chemokine playing an important role in the restriction of viral spread. A time- and dose-dependent increase in IP-10 is found upon activation of viral receptors expressed on mesothelial cells, which provides novel evidence for a link between viral infections and inflammation of serous membranes.

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