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Pediatr Neurol. 2010 Dec;43(6):431-4. doi: 10.1016/j.pediatrneurol.2010.06.008.

Henoch-Schönlein purpura in a child with Guillain-Barré syndrome.

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  • 1Department of General Pediatrics, Nihon University Nerima Hikarigaoka Hospital, Nihon University School of Medicine, Tokyo, Japan.


A case of Henoch-Schönlein purpura with Guillain-Barré syndrome in a 3-year-old-girl is presented. This association is extremely rare. During the course of Guillain-Barré syndrome, a decrease in plasma factor XIII activity was noted. When the Guillain-Barré symptoms improved, the factor XIII activity returned to normal. In the present case of Henoch-Schönlein purpura complicated by Guillain-Barré syndrome, the factor XIII level was measured, a novel feature of this study. The findings suggest the involvement of factor XIII, which is characteristically involved in Henoch-Schönlein purpura, also is involved in the associated Guillain-Barré syndrome.

Copyright © 2010 Elsevier Inc. All rights reserved.

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