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    Mol Cell Biol. 1990 Apr;10(4):1793-8.

    Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.

    Drivas GT, Shih A, Coutavas E, Rush MG, D'Eustachio P.

    Source

    Department of Biochemistry, New York University School of Medicine, New York 10016.

    Abstract

    A mixed-oligonucleotide probe was used to identify four ras-like coding sequences in a human teratocarcinoma cDNA library. Two of these sequences resembled the rho genes, one was closely related to H-, K-, and N-ras, and one shared only the four sequence domains that define the ras gene superfamily. Homologs of the four genes were found in genomic DNA from a variety of mammals and from chicken. The genes were transcriptionally active in a range of human cell types.

    PMID:
    2108320
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC362288
    Free PMC Article

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