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Dev Cell. 2010 Nov 16;19(5):649-50. doi: 10.1016/j.devcel.2010.11.001.

Tuning in to noise: epigenetics and intangible variation.

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  • 1Epigenetics Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland 4006, Australia.

Abstract

In this special issue of Developmental Cell, we discuss the role of chromatin in phenotypic variation as a counterpoint to the reviews on chromatin dynamics in development and cancer. We highlight some recent work on the role of chromatin in transcriptional noise in yeast and Caenorhabditis elegans and consider the implications in understanding intangible variation or developmental noise in mammals.

Copyright © 2010 Elsevier Inc. All rights reserved.

PMID:
21074715
[PubMed - indexed for MEDLINE]
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