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Phys Med Biol. 2010 Nov 21;55(22):6857-66. doi: 10.1088/0031-9155/55/22/016. Epub 2010 Nov 3.

Integration of image exposure time into a modified laser speckle imaging method.

Author information

  • 1Optics Department, INAOE, Puebla, Mexico. jcram@inaoep.mx

Abstract

Speckle-based methods have been developed to characterize tissue blood flow and perfusion. One such method, called modified laser speckle imaging (mLSI), enables computation of blood flow maps with relatively high spatial resolution. Although it is known that the sensitivity and noise in LSI measurements depend on image exposure time, a fundamental disadvantage of mLSI is that it does not take into account this parameter. In this work, we integrate the exposure time into the mLSI method and provide experimental support of our approach with measurements from an in vitro flow phantom.

PMID:
21048287
[PubMed - indexed for MEDLINE]
PMCID:
PMC3311822
Free PMC Article

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