Urinary lithiasis and idiopathic hypercalciuria: the importance of dietary intake evaluation

Int Braz J Urol. 2010 Sep-Oct;36(5):557-62. doi: 10.1590/s1677-55382010000500005.

Abstract

Purpose: To evaluate food intake of patients with urinary lithiasis and idiopathic hypercalciuria (IH).

Materials and methods: Between August 2007 and June 2008, 105 patients with lithiasis were distributed into 2 groups: Group 1 (n = 55)--patients with IH (urinary calcium excretion > 250 mg in women and 300 mg in men with normal serum calcium); Group 2 (n = 50)--normocalciuria (NC) patients. Inclusion criteria were: age over 18, normal renal function (creatinine clearance ≥ 60 mL/min), absent proteinuria and negative urinary culture. Pregnant women, patients with some intestinal pathology, chronic diarrhea or using corticoids were excluded. The protocol of metabolic investigation was based on non-consecutive collection of two 24-hour samples for dosages of: calcium, sodium, uric acid, citrate, oxalate, magnesium and urinary volume. Food intake was evaluated through the quantitative method of Dietary Register of three days.

Results: Urinary excretion of calcium (433.33 ± 141.92 vs. 188.93 ± 53.09), sodium (280.08 ± 100.94 vs. 200.44.93 ± 65.81), uric acid (880.63 ± 281.50 vs. 646.74 ± 182.76) and magnesium (88.78 ± 37.53 vs. 64.34 ± 31.84) was significantly higher in the IH group in comparison to the NC group (p < 0.05). As regards the nutritional composition of food intake of IH and NC groups, there was no statistical significant difference in any nutrient evaluated.

Conclusion: In our study, no difference was observed in the food intake of patients with urinary lithiasis and IH or NC.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Body Mass Index
  • Calcium / urine
  • Diet*
  • Eating*
  • Female
  • Humans
  • Hypercalciuria / metabolism*
  • Lithiasis / metabolism*
  • Magnesium / urine
  • Male
  • Middle Aged
  • Sodium / urine
  • Statistics, Nonparametric
  • Time Factors
  • Uric Acid / urine
  • Urinary Calculi

Substances

  • Uric Acid
  • Sodium
  • Magnesium
  • Calcium