Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Opt Lett. 2010 Nov 1;35(21):3673-5. doi: 10.1364/OL.35.003673.

Single-strand DNA detection using a planar photonic-crystal-waveguide-based sensor.

Author information

  • 1Nanophotonics Technology Center, Universidad Politécnica de Valencia, Camino de Vera s/n, 46022 Valencia, Spain. vertocca@ntc.upv.es

Abstract

We report an experimental demonstration of single-strand DNA (ssDNA) detection at room temperature using a photonic-crystal-waveguide-based optical sensor. The sensor surface was previously biofunctionalized with ssDNA probes to be used as specific target receptors. Our experiments showed that it is possible to detect these hybridization events using planar photonic-crystal structures, reaching an estimated detection limit as low as 19.8 nM for the detection of the complementary DNA strand.

PMID:
21042387
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Optical Society of America
    Loading ...
    Write to the Help Desk