Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Science. 2010 Oct 29;330(6004):628-9. doi: 10.1126/science.1191044.

Paramutation's properties and puzzles.

Author information

  • BIO5 Institute, Department of Plant Sciences, University of Arizona, Tucson, AZ 85719, USA. chandler@ag.arizona.edu

Abstract

Paramutation refers to the process by which homologous DNA sequences communicate in trans to establish meiotically heritable expression states. Although mechanisms are unknown, current data are consistent with the hypothesis that the establishment and heritable transmission of specific chromatin states underlies paramutation. Transcribed, noncoding tandem repeats and proteins implicated in RNA-directed transcriptional silencing in plants and yeast are required for paramutation, yet the specific molecules mediating heritable silencing remain to be determined.

PMID:
21030647
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Write to the Help Desk