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Diabetes Care. 2011 Jan;34(1):184-6. doi: 10.2337/dc10-0602. Epub 2010 Oct 27.

Untreated type 2 diabetes and its complications are associated with subcortical infarctions.

Author information

  • 1Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA. roberts.rosebud@mayo.edu

Abstract

OBJECTIVE:

To investigate the association of type 2 diabetes with subcortical infarctions.

RESEARCH DESIGN AND METHODS:

We investigated this association in subjects with type 2 diabetes (case subjects; n = 93) and without type 2 diabetes (control subjects; n = 186), matched by age, sex, and years of education. Participants were a subset of the Mayo Clinic Study of Aging (median age 79 years) who had undergone magnetic resonance imaging.

RESULTS:

The frequency of subcortical infarctions was 39% in case subjects and 29% in control subjects (odds ratio 1.59 [95% CI 0.91-2.75]). The association was stronger in case subjects without treatment (2.60 [1.11-6.08]) and in case subjects with diabetes-related complications (1.96 [1.02-3.74]) compared with control subjects.

CONCLUSIONS:

These findings suggest that untreated type 2 diabetes and type 2 diabetes with complications are associated with subcortical infarctions.

PMID:
20980413
[PubMed - indexed for MEDLINE]
PMCID:
PMC3005470
Free PMC Article
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