Abstract

OBJECTIVES:

To evaluate the association of coffee consumption with the risk of heart failure (HF) in the Finnish population.

DESIGN:

Prospective population-based cohort study.

SETTING:

This study, which is a part of FINRISK study, was carried out in Finland.

SUBJECTS:

Study cohorts included 59,490 Finnish participants aged 25-74 years who were free of HF at baseline.

MAIN OUTCOME MEASURES:

HF (2020 men and 1807 women) during a mean follow-up of 19.2 years.

RESULTS:

Multivariable-adjusted (age, study year, body mass index, smoking, education, alcohol consumption, tea consumption, physical activity, systolic blood pressure, history of myocardial infarction, history of valvular heart disease, history of diabetes and total cholesterol) HRs (with 95% CI) of HF associated with the amount of coffee consumption daily (0, 1-2, 3-4, 5-6, 7-9 and ≥10 cups) were 1.00, 0.91 (0.71 to 1.16), 0.88 (0.70 to 1.10), 0.91 (0.73 to 1.13), 0.96 (0.76 to 1.22) and 1.02 (0.80 to 1.30) (p(trend) = 0.485) for men and 1.00, 0.73 (0.56 to 0.97), 0.77 (0.60 to 0.98), 0.68 (0.53 to 0.88), 0.80 (0.61 to 1.04) and 0.88 (0.65 to 1.19) (p(trend) = 0.007) for women, respectively. Stratification by age, smoking status, alcohol consumption, history of type 2 diabetes mellitus and body mass index gave similar results.

CONCLUSION:

Coffee consumption does not increase the risk of HF in Finnish men and women. In women, an inverse association was observed between low to moderate coffee consumption and the risk of HF.