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Nucleic Acids Res. 2011 Jan;39(Database issue):D268-71. doi: 10.1093/nar/gkq936. Epub 2010 Oct 21.

Phospho3D 2.0: an enhanced database of three-dimensional structures of phosphorylation sites.

Author information

  • 1Institute for Research in Biomedicine, Joint IRB-BSC program in Computational Biology, 08028 Barcelona, Spain. andreas.zanzoni@irbbarcelona.org

Abstract

Phospho3D is a database of three-dimensional (3D) structures of phosphorylation sites (P-sites) derived from the Phospho.ELM database, which also collects information on the residues surrounding the P-site in space (3D zones). The database also provides the results of a large-scale structural comparison of the 3D zones versus a representative dataset of structures, thus associating to each P-site a number of structurally similar sites. The new version of Phospho3D presents an 11-fold increase in the number of 3D sites and incorporates several additional features, including new structural descriptors, the possibility of selecting non-redundant sets of 3D structures and the availability for download of non-redundant sets of structurally annotated P-sites. Moreover, it features P3Dscan, a new functionality that allows the user to submit a protein structure and scan it against the 3D zones collected in the Phospho3D database. Phospho3D version 2.0 is available at: http://www.phospho3d.org/.

PMID:
20965970
[PubMed - indexed for MEDLINE]
PMCID:
PMC3013787
Free PMC Article
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