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Genome Biol. 2010;11(10):218. doi: 10.1186/gb-2010-11-10-218. Epub 2010 Oct 8.

Capturing the dynamic epigenome.

Author information

  • 1Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Abstract

Traditional methods for epigenomic analysis provide a static picture of chromatin, which is actually a highly dynamic assemblage. Recent approaches have allowed direct measurements of chromatin dynamics, providing deeper insights into processes such as transcription, DNA replication and epigenetic inheritance.

PMID:
20959022
[PubMed - indexed for MEDLINE]
PMCID:
PMC3218653
Free PMC Article

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