Adjuvant therapy with methylene blue in the treatment of right ventricular failure after pulmonary embolectomy

Heart Lung Circ. 2011 Apr;20(4):234-6. doi: 10.1016/j.hlc.2010.08.018. Epub 2010 Oct 16.

Abstract

Severe pulmonary embolism often leads to right ventricular failure after surgical embolectomy secondary to ischaemia reperfusion injury and acute lung injury (ALI). Acute right ventricular dysfunction is traditionally treated with inotropes and vasopressors to maintain cardiac output and coronary perfusion as well as selective pulmonary vasodilators to provide right ventricular afterload reduction. We report the first case of utilisation of methylene (MB) in a patient with acute right ventricular failure and vasoplegic shock after surgical pulmonary embolectomy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Chemotherapy, Adjuvant / methods
  • Embolectomy*
  • Enzyme Inhibitors / administration & dosage*
  • Humans
  • Male
  • Methylene Blue / administration & dosage*
  • Pulmonary Embolism / surgery
  • Vasoplegia / drug therapy*
  • Vasoplegia / etiology
  • Ventricular Dysfunction, Right / drug therapy*
  • Ventricular Dysfunction, Right / etiology

Substances

  • Enzyme Inhibitors
  • Methylene Blue