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    Structure. 2010 Oct 13;18(10):1222-3.

    The talin FERM domain is not so FERM.

    Source

    Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK. iain.campbell@bioch.ox.ac.uk

    Abstract

    The structure of the head domain of talin, an intracellular activator of integrin membrane adhesion receptors, has been solved by Elliott et al. (2010). A FERM domain can be identified in the head from sequence comparisons but, rather than having a compact structure of three subdomains, it has linear arrangement of four subdomains.

    Copyright © 2010 Elsevier Ltd. All rights reserved.

    PMID:
    20947007
    [PubMed]

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