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Opt Express. 2010 Aug 30;18(18):19413-28. doi: 10.1364/OE.18.019413.

Automatic segmentation of seven retinal layers in SDOCT images congruent with expert manual segmentation.

Chiu SJ, Li XT, Nicholas P, Toth CA, Izatt JA, Farsiu S.

Source

Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA. stephanie.chiu@duke.edu

Abstract

Segmentation of anatomical and pathological structures in ophthalmic images is crucial for the diagnosis and study of ocular diseases. However, manual segmentation is often a time-consuming and subjective process. This paper presents an automatic approach for segmenting retinal layers in Spectral Domain Optical Coherence Tomography images using graph theory and dynamic programming. Results show that this method accurately segments eight retinal layer boundaries in normal adult eyes more closely to an expert grader as compared to a second expert grader.

PMID:: 20940837; [PubMed - indexed for MEDLINE]
PMCID:: PMC3408910

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R21 EY019411/EY/NEI NIH HHS/United States

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