Antimicrobial stewardship: an evidence-based, antimicrobial self-assessment toolkit (ASAT) for acute hospitals

J Antimicrob Chemother. 2010 Dec;65(12):2669-73. doi: 10.1093/jac/dkq367. Epub 2010 Oct 8.

Abstract

Objectives: To describe the methodology in developing an antimicrobial self-assessment toolkit (ASAT).

Methods: The ASAT was developed through a National Pharmacy Reference Group using an evidence-based approach of published information and national reports to identify criteria for inclusion. These were subdivided into domains that addressed: 1) Antimicrobial management within the Trust-structures and lines of responsibility and accountability-high-level notification to the Board. 2) Operational delivery of an antimicrobial strategy-operational standards of good antimicrobial stewardship. 3) Risk assessment for antimicrobial chemotherapy. 4) Clinical governance assurance. 5) Education and training-training needs and delivery of education and training for all who issue, prescribe and administer antimicrobials. 6) Antimicrobial pharmacist-systems in place for ensuring their optimum use. 7) Patients, Carers and the Public-information needs of patients, carers and the public.

Results: A web-based toolkit was developed using information from national reports and guidance on antimicrobial stewardship. The toolkit offers a checklist for hospitals to self-assess their organizations' levels of antimicrobial stewardship.

Conclusions: The ASAT offers a web-enabled, version-controlled instrument for the assessment of antimicrobial stewardship in acute hospitals. It may offer a sensitive instrument to assess longitudinal progress on antimicrobial stewardship in an individual institution or act as a benchmark with similar organizations. Further work is ongoing to evaluate and further refine the ASAT.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Decision Support Systems, Clinical / instrumentation*
  • Decision Support Systems, Clinical / organization & administration
  • Drug Utilization / standards
  • Evidence-Based Medicine*
  • Hospitals / standards*
  • Humans
  • Infection Control / methods
  • Internet*
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians' / standards*
  • Program Development / methods

Substances

  • Anti-Bacterial Agents