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    J Bacteriol. 2010 Dec;192(24):6492-3. doi: 10.1128/JB.01023-10. Epub 2010 Oct 8.

    Genome sequence of the polysaccharide-degrading, thermophilic anaerobe Spirochaeta thermophila DSM 6192.

    Angelov A, Liebl S, Ballschmiter M, Bömeke M, Lehmann R, Liesegang H, Daniel R, Liebl W.

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    Department of Genomic and Applied Microbiology, Göttingen Genomics Laboratory, Institute of Microbiology and Genetics, Georg-August-Universität, Grisebachstr 8, D-37077 Goettingen, Germany.

    Abstract

    Spirochaeta thermophila is a thermophilic, free-living anaerobe that is able to degrade various α- and β-linked sugar polymers, including cellulose. We report here the complete genome sequence of S. thermophila DSM 6192, which is the first genome sequence of a thermophilic, free-living member of the Spirochaetes phylum. The genome data reveal a high density of genes encoding enzymes from more than 30 glycoside hydrolase families, a noncellulosomal enzyme system for (hemi)cellulose degradation, and indicate the presence of a novel carbohydrate-binding module.

    PMID:
    20935097
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC3008529
    Free PMC Article

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