Display Settings:


Send to:

Choose Destination
See comment in PubMed Commons below
Adv Exp Med Biol. 2010;688:165-84.

Gangliosides as regulators of cell membrane organization and functions.

Author information

  • 1Center of Excellence on Neurodegenerative Diseases, Department of Medical Chemistry, University of Milan, Segrate, Italy.


Gangliosides, characteristic complex lipids present in the external layer of plasma membranes, deeply influence the organization of the membrane as a whole and the function of specific membrane associated proteins due to lipid-lipid and lipid-protein lateral interaction. Here we discuss the basis for the membrane-organizing potential of gangliosides, examples of ganglioside-regulated membrane protein complexes and the mechanisms for the regulation of ganglioside membrane composition.

[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk