Immune response to varicella vaccine in children with atopic dermatitis compared with nonatopic controls

J Allergy Clin Immunol. 2010 Dec;126(6):1306-7.e2. doi: 10.1016/j.jaci.2010.08.010.

Abstract

Atopic dermatitis subjects and controls had similar cellular immune responses to Varicella vaccine. Atopic dermatitis subjects with a history of eczema herpeticum made high levels of Varicella specific IgE.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Antigens, Viral / immunology
  • CD4-Positive T-Lymphocytes / immunology
  • CD4-Positive T-Lymphocytes / metabolism*
  • CD4-Positive T-Lymphocytes / pathology
  • CD4-Positive T-Lymphocytes / virology
  • Cells, Cultured
  • Chickenpox Vaccine / administration & dosage*
  • Chickenpox Vaccine / adverse effects
  • Child, Preschool
  • Dermatitis, Atopic / blood
  • Dermatitis, Atopic / complications
  • Dermatitis, Atopic / immunology*
  • Dermatitis, Atopic / physiopathology
  • Disease Progression
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Herpesviridae Infections / blood
  • Herpesviridae Infections / complications
  • Herpesviridae Infections / immunology*
  • Herpesviridae Infections / physiopathology
  • Herpesvirus 3, Human / immunology*
  • Herpesvirus 3, Human / pathogenicity
  • Humans
  • Immunoglobulin E / blood
  • Infant
  • Interferon-gamma / metabolism
  • Kaposi Varicelliform Eruption
  • Lymphocyte Activation
  • Male

Substances

  • Antigens, Viral
  • Chickenpox Vaccine
  • Immunoglobulin E
  • Interferon-gamma