Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Trends Genet. 1990 Dec;6(12):410-6.

Centromeres of mammalian chromosomes.

Author information

  • Department of Genetics, Stanford University, CA 94305.

Abstract

The centromere is the major cis-acting genetic locus involved in chromosome segregation in mitosis and meiosis. The mammalian centromere is characterized by large amounts of tandemly repeated satellite DNA and by a number of specific centromere proteins, at least one of which has been shown to interact directly with centromeric satellite DNA sequences. Although direct functional assays of chromosome segregation are still lacking, the data are most consistent with a structural and possibly functional role for satellite DNA in the mammalian centromere.

PMID:
2087784
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk