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J Clin Rheumatol. 2010 Oct;16(7):332-4. doi: 10.1097/RHU.0b013e3181f4cd92.

Abatacept therapy for rheumatoid arthritis in the setting of hepatitis C infection.

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  • 1Dallas VA Medical Center and University of Texas Southwestern Medical Center, Dallas, TX, USA.


Chronic hepatitis C in the setting of rheumatoid arthritis may be an obstacle to optimal management because of potential hepatotoxicity and adverse effects from immune suppression in these patients with a chronic infection. There are no reports in the literature discussing the use of abatacept, a T-cell costimulatory blocker, in patients with chronic hepatitis C. This article is the first report to describe the use of abatacept in 2 patients with rheumatoid arthritis and concomitant hepatitis C with favorable outcome.

[PubMed - indexed for MEDLINE]
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