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J Cell Biol. 2010 Sep 20;190(6):953-63. doi: 10.1083/jcb.201006020.

The cell biology of vision.

Author information

  • 1Dyson Vision Research Institute, Department of Ophthalmology, Weill Cornell Medical College, New York, NY 10065, USA. chsung@med.cornell.edu

Abstract

Humans possess the remarkable ability to perceive color, shape, and motion, and to differentiate between light intensities varied by over nine orders of magnitude. Phototransduction--the process in which absorbed photons are converted into electrical responses--is the first stage of visual processing, and occurs in the outer segment, the light-sensing organelle of the photoreceptor cell. Studies of genes linked to human inherited blindness have been crucial to understanding the biogenesis of the outer segment and membrane-trafficking of photoreceptors.

PMID:
20855501
[PubMed - indexed for MEDLINE]
PMCID:
PMC3101587
Free PMC Article

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