Format

Send to:

Choose Destination
See comment in PubMed Commons below
Vaccine. 2010 Oct 28;28(46):7389-95. doi: 10.1016/j.vaccine.2010.09.009. Epub 2010 Sep 17.

Vaccine preventable diseases in returned international travelers: results from the GeoSentinel Surveillance Network.

Author information

  • 1Tropical Disease Unit, UHN-Toronto General Hospital, 200 Elizabeth Street, North Wing, Toronto, ON, M5G 2C4, Canada. andrea.boggild@utoronto.ca

Abstract

Vaccine preventable diseases (VPDs) threaten international travelers, but little is known about their epidemiology in this group. We analyzed records of 37,542 ill returned travelers entered into the GeoSentinel Surveillance Network database. Among 580 (1.5%) with VPDs, common diagnoses included enteric fever (n=276), acute viral hepatitis (n=148), and influenza (n=70). Factors associated with S. typhi included VFR travel (p<0.016) to South Central Asia (p<0.001). Business travel was associated with influenza (p<0.001), and longer travel with hepatitis A virus (p=0.02). 29% of those with VPDs had pre-travel consultations. At least 55% of those with VPDs were managed as inpatients, compared to 9.5% of those with non-VPDs. Three deaths occurred; one each due to pneumococcal meningitis, S. typhi, and rabies. VPDs are significant contributors to morbidity and potential mortality in travelers. High rates of hospitalization make them an attractive target for pre-travel intervention.

Copyright © 2010 Elsevier Ltd. All rights reserved.

PMID:
20851081
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk