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Middle East Afr J Ophthalmol. 2010 Jul;17(3):210-6. doi: 10.4103/0974-9233.65494.

Exoresection and endoresection for uveal melanoma.

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  • 1Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey.

Abstract

Surgical resection of uveal melanomas is an alternative eye-salvaging approach to the more commonly used irradiation techniques. There are two surgical resection techniques: Transscleral resection or "Exoresection" via a partial lamellar sclerouvectomy and "Endoresection" via a pars plana vitrectomy. While exoresection is more applicable to anteriorly located tumors with ciliary body and/or iris involvement, endoresection is more suitable for posteriorly located tumor without ciliary body involvement. Both approaches are suitable for large tumors with >8 mm in thickness. In general, eyes containing these large tumors have a very dismal prognosis regarding long-term visual function, eye retention, and irradiation-induced side effects. By removing the tumor burden from the eye, histopathologic and cytogenetic information of the tumor is available and complications associated with the so-called toxic tumor syndrome are avoided. However, both types of surgical resection are challenging surgical procedures, bearing the risk of early and late postoperative complications.

KEYWORDS:

Endoresection; Exoresection; Melanoma; Nevus; Partial Lamellar Sclerouvectomy

PMID:
20844676
[PubMed]
PMCID:
PMC2934712
Free PMC Article
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