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J Exp Med. 2010 Sep 27;207(10):2053-63. doi: 10.1084/jem.20101664. Epub 2010 Sep 13.

Type I interferon: friend or foe?

Author information

  • 1Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702, USA. trinchig@mail.nih.gov

Abstract

Although the role of type I interferon (IFN) in the protection against viral infections has been known and studied for decades, its role in other immunologically relevant scenarios, including bacterial infections, shock, autoimmunity, and cancer, is less well defined and potentially much more complicated.

PMID:
20837696
[PubMed - indexed for MEDLINE]
PMCID:
PMC2947062
Free PMC Article
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