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Am J Surg. 2011 Apr;201(4):486-91. doi: 10.1016/j.amjsurg.2010.02.003. Epub 2010 Sep 15.

The influence of race on the development of acute lung injury in trauma patients.

Author information

  • 1Department of Surgery, University of California, San Francisco at San Francisco, General Hospital, 94143, USA.

Abstract

BACKGROUND:

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are sequelae of severe trauma. It is unknown if certain races are at greater risk of developing ALI/ARDS, and once established, if there are racial differences in the severity of lung injury or mortality.

METHODS:

Retrospective cohort study of 4,397 trauma patients (1,831 Caucasians, 871 African-Americans, 886 Hispanics, and 809 Asian/Pacific Islanders) requiring intensive care unit (ICU) admission between 1996 and 2007 at an urban Level I trauma center.

RESULTS:

African-American patients were most likely to present in shock with penetrating trauma and receive a massive transfusion. The incidence of ALI/ARDS was similar by race (P = .99). Among patients who developed ALI/ARDS, there was no evidence to support a difference in partial pressure of oxygen in arterial blood to fraction of inspired oxygen (Pao(2)/Fio(2)) (P = .33), lung injury score (P = .67), or mortality (P = .78) by race.

CONCLUSIONS:

Despite differences in baseline characteristics, the incidence of ALI/ARDS, severity of lung injury, and mortality were similar by race.

Copyright © 2011 Elsevier Inc. All rights reserved.

PMID:
20832050
[PubMed - indexed for MEDLINE]
PMCID:
PMC3006033
Free PMC Article

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