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Department of Neonatology, Beilinson Medical Center, Petah Tiqva, Sackler School of Medicine, Tel-Aviv University, Israel.
Twenty out of 303 ventilated low birth weight infants, hospitalized in the Beilinson Medical Center's Intensive Care Unit, during the years 1984-1986, developed pulmonary interstitial emphysema. Eighteen infants had very low birth weight (less than 1500 grams) and 17 were less than 30 weeks' gestation. The mean birth weight was 987 +/- 311 and mean gestational age 27.7 +/- 2.5. Eight infants survived the pulmonary disease. There were no significant differences in the neonatal parameters between infants who died or survived. However, the survivors had a significantly lower maximal peak inspiratory pressure and FiO2 on the first day of ventilation. The incidence of pneumothorax and asphyxia was the same in both groups.
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