Arch Pediatr. 2010 Sep;17 Suppl 4:S145-9.

[Description and investigation of an outbreak of extended-spectrum beta-lactamase producing Escherichia coli strain in a neonatal unit].

[Article in French]

Quinet B, Mitanchez D, Salauze B, Carbonne A, Bingen E, Fournier S, Moissenet D, Vu-Thien H.

Source

Service de Pédiatrie Générale, Hôpital Armand Trousseau, 26, Avenue du Docteur Arnold-Netter, 75571 Paris cedex 12, France. beatrice.quinet@trs.aphp.fr

Abstract

An outbreak of colonization and infection with an Escherichia coli strain producing extended-spectrum beta-lactamase (ESBL) occurred in a neonatal unit : a high rate of cases was observed, 27/59 neonates were colonized : one of them developed meningitis with favourable outcome and another baby developed conjunctivitis. Despite intensive efforts to control the outbreak by standard methods of hand hygiene, patients screening and isolation, the spread was uncontrolled and the unit was closed to all admission in order to stop the outbreak. The investigation was not able to identify a single outbreak's source. Emergence and spread of ESBL producing E. coli strains from community and hospital acquired infections are a significant public health problem with difficult choice of treatment for serious infections.

PMID:: 20826323; [PubMed - indexed for MEDLINE]

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