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Bioorg Khim. 2010 Jul-Aug;36(4):437-81.

[Modification of nucleic acids using [3+2] dipolar cycloaddition of azides and alkynes].

[Article in Russian]

Abstract

The use of the reaction of azide and alkyne cycloaddition for the synthesis of nucleic acid conjugates and DNA oligomer analogues is considered. The data on chemical and enzymatic techniques of azides and alkynes introduction into DNA are summarized.

PMID:
20823915
[PubMed - indexed for MEDLINE]
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