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Cell. 2010 Sep 3;142(5):679-81. doi: 10.1016/j.cell.2010.08.024.

'Fore brain: a hint of the ancestral cortex.

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  • 1Neurosciences Program, Stanford University, Stanford, CA 94305, USA.


By combining gene expression profiling with image registration, Tomer et al. (2010) find that the mushroom body of the segmented worm Platynereis dumerilii shares many features with the mammalian cerebral cortex. The authors propose that the mushroom body and cortex evolved from the same structure in the common ancestor of vertebrates and invertebrates.

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