Int Psychogeriatr. 2011 Mar;23(2):325-7.

Bupropion in the treatment of depression in Parkinson's disease.

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IV Department of Psychiatry, Institute of Psychiatry and Neurology, Warsaw, Poland.

Abstract

A 78-year-old female with a nine-year history of depression was hospitalized due to worsening depression and symptoms associated with Parkinson's disease (PD). Her motor abilities improved on levodopa and the depression improved after a trial of bupropion, following unsuccessful treatment with other antidepressants. We found four reports on successful treatment of depression in PD with bupropion. However, no controlled double-blind studies have been conducted so clinicians should be cautious when administering bupropion in depression in PD.

PMID:: 20809995; [PubMed - indexed for MEDLINE]

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