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J Neuroinflammation. 2010 Aug 17;7:47. doi: 10.1186/1742-2094-7-47.

Hypothalamic abnormalities and Parkinsonism associated with H1N1 influenza infection.

Author information

  • 1Department of Neurology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México DF, México. gonzalezduarte@aol.com

Abstract

OBJECTIVE:

To describe a case of a young adult with severe H1N1 influenza illness associated with hypothalamic abnormalities and post-influenza parkinsonism.

DESIGN:

Case report.

PATIENT:

A 22-year-old woman with H1N1 influenza infection developed encephalopathy followed by diverse hypothalamic dysfunction manifestations, sleeplessness, and persistent parkinsonian features.

RESULTS:

CSF analysis, brain imaging and EEG ruled out hypoxic brain injury or other illnesses.

CONCLUSIONS:

A number of viruses have been associated with both acute and chronic parkinsonism. A link between parkinsonism and influenza viruses is somewhat controversial. This is the first reported case of parkinsonism following an H1N1 influenza infection.

PMID:
20716355
[PubMed - indexed for MEDLINE]
PMCID:
PMC2933605
Free PMC Article

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