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Ir J Med Sci. 2011 Mar;180(1):115-9. doi: 10.1007/s11845-010-0550-y. Epub 2010 Aug 17.

Hypovitaminosis D in a healthy female population, aged from 40 to 85 years, in the west of Ireland.

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  • 1Biochemistry Laboratory, Galway University Hospital, Newcastle Road, Galway, Ireland.



Increasing attention has been focused on diseases associated with ageing, as the mean age of the population in developed countries increases. Vitamin D and parathyroid hormone play key roles in calcium homeostasis, which is integral to skeletal health.


To assess the vitamin D status of healthy, community dwelling, middle-aged and older females.


General biochemistry and bone profiles, including ALP, PTH and 25(OH)D, were determined.


Of 143 healthy white women receiving no supplementation or bone modifying treatments, 47% were vitamin D insufficient (<50 nmol/L) and only 4% were sufficient for the time of year. There was no statically significant correlation between age and 25(OH)D concentrations; neither was there a statistically significant seasonal variation in 25(OH)D levels noted.


Vitamin D status should be assessed more often in middle-aged and older females. Expected age-related and seasonal variations in 25(OH)D levels were not confirmed in this study.

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