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Ir J Med Sci. 2011 Mar;180(1):115-9. doi: 10.1007/s11845-010-0550-y. Epub 2010 Aug 17.

Hypovitaminosis D in a healthy female population, aged from 40 to 85 years, in the west of Ireland.

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  • 1Biochemistry Laboratory, Galway University Hospital, Newcastle Road, Galway, Ireland. eleanorlardner@gmail.com

Abstract

BACKGROUND:

Increasing attention has been focused on diseases associated with ageing, as the mean age of the population in developed countries increases. Vitamin D and parathyroid hormone play key roles in calcium homeostasis, which is integral to skeletal health.

AIMS:

To assess the vitamin D status of healthy, community dwelling, middle-aged and older females.

METHODS:

General biochemistry and bone profiles, including ALP, PTH and 25(OH)D, were determined.

RESULTS:

Of 143 healthy white women receiving no supplementation or bone modifying treatments, 47% were vitamin D insufficient (<50 nmol/L) and only 4% were sufficient for the time of year. There was no statically significant correlation between age and 25(OH)D concentrations; neither was there a statistically significant seasonal variation in 25(OH)D levels noted.

CONCLUSION:

Vitamin D status should be assessed more often in middle-aged and older females. Expected age-related and seasonal variations in 25(OH)D levels were not confirmed in this study.

PMID:
20714939
[PubMed - indexed for MEDLINE]
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