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Indian J Psychiatry. 2006 Oct;48(4):254-7. doi: 10.4103/0019-5545.31559.

The course of bipolar disorder in rural India.

Author information

  • 1Assistant Professor, Department of Psychiatry, National Institute of Mental Health and Neuro Sciences (NIMHANS), Hosur Road, Bangalore 560029, Karnataka.

Abstract

AIM:

To examine the naturalistic course of bipolar disorder in a rural, community-based, partially treated cohort.

METHODS:

All patients diagnosed with bipolar disorder during an epidemiological survey (n=34) in a rural area in India were followed longitudinally using standardized instruments, and the life-chart method used to examine their course.

RESULTS:

Seven (26%) of the 27 patients evaluated directly had not received any treatment whatsoever. Four patients (15%) had experienced rapid-cycling at some time; patients without rapid-cycling had experienced a mean 0.22 episodes/year. Episodes of mania accounted for 72% of all episodes. None of the variables examined appeared to predict the total number of episodes experienced by individual patients, although rapid-cycling occurred significantly more often if the patients had not received any psychopharmacological treatment.

CONCLUSIONS:

A mania-predominant course was observed in this small cohort, similar to reports from other developing countries.

KEYWORDS:

Bipolar disorder; longitudinal follow-up; mania; rural

PMID:
20703347
[PubMed]
PMCID:
PMC2915598
Free PMC Article
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