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    J Clin Exp Neuropsychol. 2011 Feb;33(2):176-86. Epub 2010 Aug 6.

    Discounting of delayed rewards and executive dysfunction in individuals infected with hepatitis C.

    Source

    Northwest Hepatitis C Resource Center, Portland VA Medical Center, Portland, OR 97239, USA. marilyn.huckans@va.gov

    Abstract

    OBJECTIVE:

    Determine whether adults with hepatitis C (HCV), regardless of substance use disorder, are more likely to discount delayed rewards than adults without hepatitis C, and explore the relationship between delay discounting and neuropsychological functioning.

    METHODS:

    Procedures included clinical interviews, neuropsychological testing, and a delay discounting task.

    RESULTS:

    Regardless of substance abuse history, adults with hepatitis C were significantly more likely to choose smaller immediate rewards over larger delayed rewards. Delay discounting correlated with performance on executive functioning tasks.

    CONCLUSIONS:

    Increased discounting is associated with broad executive dysfunction, suggesting that HCV-associated executive dysfunction may lead to altered decision-making style.

    PMID:
    20694872
    [PubMed - indexed for MEDLINE]

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