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Cell. 2010 Aug 6;142(3):358-60. doi: 10.1016/j.cell.2010.07.029.

Noncoding RNAs: the missing "linc" in p53-mediated repression.

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  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.


The tumor suppressor protein p53 coordinates the cellular response to stress through regulation of gene expression. Now, Huarte et al. (2010) identify a long intergenic noncoding RNA as a new player in p53-mediated repression of genes involved in apoptosis.

Copyright 2010 Elsevier Inc. All rights reserved.

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