Fatty acid beta-oxidation-dependent bioactivation of 5,6-dichloro-4-thia-5-hexenoate and analogs in isolated rat hepatocytes

Adv Exp Med Biol. 1991:283:281-4. doi: 10.1007/978-1-4684-5877-0_32.
No abstract available

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Biotransformation
  • Cell Survival / drug effects
  • Fatty Acids / metabolism*
  • In Vitro Techniques
  • Liver / drug effects
  • Liver / metabolism*
  • Male
  • Oxidation-Reduction
  • Oxygen Consumption / drug effects
  • Propionates / pharmacokinetics*
  • Propionates / toxicity
  • Rats

Substances

  • Fatty Acids
  • Propionates
  • S-(1,2-dichlorovinyl)-3-mercaptopropionic acid