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J Clin Microbiol. 2010 Oct;48(10):3794-6. doi: 10.1128/JCM.00491-10. Epub 2010 Aug 4.

Unusual "flesh-eating" strain of Escherichia coli.

Author information

  • 1Intensive Care Unit, Cochin University Hospital, 75014 Assistance Publique Hôpitaux de Paris, Paris, France. david.grimaldi@cch.aphp.fr

Abstract

We report an exceptional case of life-threatening Escherichia coli-induced necrotizing fasciitis. A combined host-pathogen genetic analysis explained the phenotype: the host displayed a susceptibility to intravascular coagulation, and the strain was capable of producing a necrotic toxin (cytotoxic necrotizing factor 1), showing how E. coli can be a dermonecrotic pathogen.

PMID:
20686096
[PubMed - indexed for MEDLINE]
PMCID:
PMC2953099
Free PMC Article

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FIG. 1.
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