Format

Send to

Choose Destination
See comment in PubMed Commons below
Br J Psychiatry. 2010 Aug;197(2):106-13. doi: 10.1192/bjp.bp.109.069674.

Aetiology of fatigue in Sri Lanka and its overlap with depression.

Author information

  • 1MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, De Crespigny Park, London SE5 8AF. harriet.ball@kcl.ac.uk

Abstract

BACKGROUND:

Fatigue is a common symptom in Western high-income countries but is often medically unexplained and little is known about its presentation in other populations.

AIMS:

To explore the epidemiology and aetiology of fatigue in Sri Lanka, and of its overlap with depression.

METHOD:

A total of 4024 randomly selected twins from a population-based register in Sri Lanka (Colombo district) completed home interviews including the Chalder Fatigue Questionnaire.

RESULTS:

The prevalence of fatigue was similar to that in other countries, although prolonged fatigue may be less common. There was substantial comorbidity with a screen for lifetime depression. Non-shared environmental factors made the largest contributions, although genetic/family factors also contributed. The aetiology appeared consistent across the spectrum of severity.

CONCLUSIONS:

The aetiology of fatigue is broadly similar in Sri Lanka and Western high-income countries. Abnormal experiences of fatigue appear to be the extreme form of more common fatigue, rather than representing independent entities with different genetic or environmental risk factors.

Comment in

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk