Trends Parasitol. 2011 Jan;27(1):31-9. Epub 2010 Jul 19.

A genotype and phenotype database of genetically modified malaria-parasites.

Janse CJ, Kroeze H, van Wigcheren A, Mededovic S, Fonager J, Franke-Fayard B, Waters AP, Khan SM.

Source

Leiden Malaria Research Group, Parasitology, Leiden University Medical Centre (LUMC), Albinusdreef 2, 2333 ZA, Leiden, The Netherlands. c.j.janse@lumc.nl

Abstract

The RMgm database, www.pberghei.eu, is a web-based, manually curated, repository containing information on genetically modified rodent-malaria parasites. It provides easy and rapid access to information on the genotype and phenotype of mutant and reporter parasites. The database also contains information on unpublished mutants without a clear phenotype and negative trials to disrupt genes. Information can be searched using pre-defined key features, such as phenotype, life-cycle stage, gene model, gene-tags and mutations. The information relating to the mutants is reciprocally linked to PlasmoDB and GeneDB. Access to mutant-parasite information, and gene function/ontology inferred from mutant phenotypes provides a timely resource aimed at enhancing research into Plasmodium gene function and (systems) biology.

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Trends Parasitol. 2011 Jan;27(1):1-2.

PMID:: 20663715; [PubMed - indexed for MEDLINE]

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