Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Pediatr Hematol Oncol. 2010 Aug;32(6):e236-7. doi: 10.1097/MPH.0b013e3181e75759.

Familial childhood monosomy 7 and associated myelodysplasia.

Author information

  • 1Department of Pathology, University of Illinois, College of Medicine, Chicago 60612, USA. sgaitond@uic.edu

Abstract

SUMMARY:

Familial monosomy 7 is defined as bone marrow monosomy 7 occurring as a sole cytogenetic abnormality affecting 2 or more siblings. It manifests usually in childhood with neurologic disorder (cerebellar ataxia or atrophy) and/or hematologic disorder (marrow hypoplasia, myelodysplasia, acute myeloid leukemia, or pancytopenia). Partial or complete monosomy 7 with hematologic disorder has been reported in 13 families/pedigrees to date. Here we report the 14th family.

PMID:
20661156
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Lippincott Williams & Wilkins
    Loading ...
    Write to the Help Desk