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    J Gen Virol. 2010 Nov;91(Pt 11):2706-12. Epub 2010 Jul 21.

    Tick-borne encephalitis virus in ticks in Finland, Russian Karelia and Buryatia.

    Jääskeläinen AE, Sironen T, Murueva GB, Subbotina N, Alekseev AN, Castrén J, Alitalo I, Vaheri A, Vapalahti O.

    Source

    Infection Biology Research Program, Department of Virology, Haartman Institute, FI-00014 University of Helsinki, Finland. anu.jaaskelainen@helsinki.fi

    Abstract

    Tick-borne encephalitis (TBE) is a central nervous system infection caused by a flavivirus [tick-borne encephalitis virus (TBEV)], transmitted by Ixodes ticks and endemic in a large region in Eurasia. We collected 2411 ticks from Finland and Russia in 2003-2008, screened them for TBEV by RT-PCR and isolated and analysed eight strains belonging to all three TBEV subtypes; in addition, we obtained two European-subtype strains from human serum samples. TBEV RNA prevalence in unengorged ticks was approximately 1 % both in the northernmost TBE-endemic areas of Europe in Finland and Russian Karelia, and in Siberia in Buryatia. In Finland, both Ixodes ricinus and Ixodes persulcatus ticks were found from distinct areas and, in Russian Karelia, were overlapping in the same study site. TBEV E and NS3 gene sequences obtained showed a variability of 0-4 % within European-subtype strains, 2-9 % for Siberian-subtype strains and 3-13 % for Far Eastern-subtype strains.

    PMID:
    20660147
    [PubMed - indexed for MEDLINE]
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